{"id":34548,"date":"2024-11-26T16:46:57","date_gmt":"2024-11-26T16:46:57","guid":{"rendered":"https:\/\/bnssghealthiertogether.org.uk\/?page_id=34548"},"modified":"2025-01-16T22:41:05","modified_gmt":"2025-01-16T22:41:05","slug":"the-effectiveness-and-cost-effectiveness-of-coenzyme-q10-in-heart-failure-with-reduced-ejection-fraction-a-pragmatic-patient-centred-data-enabled-trial-in-primary-care-coral","status":"publish","type":"page","link":"https:\/\/bnssghealthiertogether.org.uk\/bn\/integrated-care-board\/research-and-evidence\/our-research-portfolio\/nihr-funded-projects\/the-effectiveness-and-cost-effectiveness-of-coenzyme-q10-in-heart-failure-with-reduced-ejection-fraction-a-pragmatic-patient-centred-data-enabled-trial-in-primary-care-coral\/","title":{"rendered":"\u09b9\u09cd\u09b0\u09be\u09b8\u09aa\u09cd\u09b0\u09be\u09aa\u09cd\u09a4 \u0987\u099c\u09c7\u0995\u09b6\u09a8 \u09ab\u09cd\u09b0\u09cd\u09af\u09be\u0995\u09b6\u09a8\u09af\u09c1\u0995\u09cd\u09a4 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\u09b9\u09ac\u09c7?<\/h2>\n<p>\u0985\u0982\u09b6\u0997\u09cd\u09b0\u09b9\u09a3\u0995\u09be\u09b0\u09c0\u09a6\u09c7\u09b0 \u09aa\u09cd\u09b0\u09b6\u09cd\u09a8\u09be\u09ac\u09b2\u09c0 \u09aa\u09c2\u09b0\u09a3 \u0995\u09b0\u09a4\u09c7 \u09ac\u09b2\u09be\u09b0 \u09ae\u09be\u09a7\u09cd\u09af\u09ae\u09c7 \u0986\u09ae\u09b0\u09be \u098f\u0987 \u09ac\u09bf\u09b7\u09af\u09bc\u099f\u09bf \u099c\u09be\u09a8\u09ac\u0964 \u09aa\u09cd\u09b0\u09b6\u09cd\u09a8\u09be\u09ac\u09b2\u09c0\u09a4\u09c7 \u09a4\u09be\u09a6\u09c7\u09b0 \u099c\u09c0\u09ac\u09a8\u09af\u09be\u09a4\u09cd\u09b0\u09be\u09b0 \u09ae\u09be\u09a8 \u098f\u09ac\u0982 \u09a6\u09c8\u09a8\u09a8\u09cd\u09a6\u09bf\u09a8 \u099c\u09c0\u09ac\u09a8 \u09b8\u09ae\u09cd\u09aa\u09b0\u09cd\u0995\u09c7 \u099c\u09bf\u099c\u09cd\u099e\u09be\u09b8\u09be \u0995\u09b0\u09be \u09b9\u09ac\u09c7 (\u0995\u09cd\u09af\u09be\u09a8\u09b8\u09be\u09b8 \u09b8\u09bf\u099f\u09bf \u0995\u09be\u09b0\u09cd\u09a1\u09bf\u0993\u09ae\u09be\u09af\u09bc\u09cb\u09aa\u09cd\u09af\u09be\u09a5\u09bf \u09aa\u09cd\u09b0\u09b6\u09cd\u09a8\u09be\u09ac\u09b2\u09c0, \u0987\u0989\u09b0\u09cb\u0995\u09b2 \u09eb \u09a1\u09be\u0987\u09ae\u09c7\u09a8\u09b6\u09a8\u09b8 \u0985\u09ab \u09b9\u09c7\u09b2\u09a5 \u09aa\u09cd\u09b0\u09b6\u09cd\u09a8\u09be\u09ac\u09b2\u09c0, \u098f\u09ac\u0982 \u09a8\u09bf\u0989 \u0987\u09af\u09bc\u09b0\u09cd\u0995 \u09b9\u09be\u09b0\u09cd\u099f \u0985\u09cd\u09af\u09be\u09b8\u09cb\u09b8\u09bf\u09af\u09bc\u09c7\u09b6\u09a8 \u09aa\u09cd\u09b0\u09b6\u09cd\u09a8\u09be\u09ac\u09b2\u09c0)\u0964.<\/p>\n<p>\u098f\u099b\u09be\u09a1\u09bc\u09be\u0993 \u098f\u0995\u099f\u09bf \u09aa\u09cd\u09b0\u09b6\u09cd\u09a8\u09aa\u09a4\u09cd\u09b0 \u09a5\u09be\u0995\u09ac\u09c7, \u09af\u09c7\u0996\u09be\u09a8\u09c7 \u099c\u09be\u09a8\u09a4\u09c7 \u099a\u09be\u0993\u09af\u09bc\u09be \u09b9\u09ac\u09c7 \u09af\u09c7 \u09b9\u09c3\u09a6\u09af\u09a8\u09cd\u09a4\u09cd\u09b0\u09c7\u09b0 \u09ac\u09bf\u0995\u09b2\u09a4\u09be \u09a4\u09be\u09a6\u09c7\u09b0 \u098f\u09ac\u0982 \u09a4\u09be\u09a6\u09c7\u09b0 \u09aa\u09b0\u09bf\u099a\u09b0\u09cd\u09af\u09be\u0995\u09be\u09b0\u09c0\u09a6\u09c7\u09b0 \u0986\u09b0\u09cd\u09a5\u09bf\u0995\u09ad\u09be\u09ac\u09c7 \u0995\u09c0\u09ad\u09be\u09ac\u09c7 \u09aa\u09cd\u09b0\u09ad\u09be\u09ac\u09bf\u09a4 \u0995\u09b0\u09c7\u0964 \u0997\u09ac\u09c7\u09b7\u09a3\u09be\u09af\u09bc \u0985\u0982\u09b6\u0997\u09cd\u09b0\u09b9\u09a3\u0995\u09be\u09b0\u09c0\u09a6\u09c7\u09b0 \u0997\u09ac\u09c7\u09b7\u09a3\u09be \u09b6\u09c1\u09b0\u09c1\u09b0 \u0986\u0997\u09c7, \u098f\u09ac\u0982 \u09a4\u09be\u09b0\u09aa\u09b0 \u09e9, \u09ec, \u09ef \u09ae\u09be\u09b8 \u0993 \u098f\u0995 \u09ac\u099b\u09b0 \u09aa\u09b0 (\u0997\u09ac\u09c7\u09b7\u09a3\u09be \u09b6\u09c7\u09b7\u09c7) \u098f\u0987 \u09aa\u09cd\u09b0\u09b6\u09cd\u09a8\u09aa\u09a4\u09cd\u09b0\u0997\u09c1\u09b2\u09cb \u09aa\u09c2\u09b0\u09a3 \u0995\u09b0\u09a4\u09c7 \u09ac\u09b2\u09be \u09b9\u09ac\u09c7\u0964.<\/p>\n<p>\u0986\u09ae\u09be\u09a6\u09c7\u09b0 \u09a7\u09be\u09b0\u09a3\u09be, \u09aa\u09cd\u09b0\u09b6\u09cd\u09a8\u09aa\u09a4\u09cd\u09b0\u0997\u09c1\u09b2\u09cb \u09aa\u09c2\u09b0\u09a3 \u0995\u09b0\u09a4\u09c7 \u09aa\u09cd\u09b0\u09be\u09af\u09bc \u09e9\u09eb \u09ae\u09bf\u09a8\u09bf\u099f \u09b8\u09ae\u09af\u09bc \u09b2\u09be\u0997\u09ac\u09c7 \u098f\u09ac\u0982 \u09aa\u09cd\u09b0\u09a4\u09bf\u099f\u09bf \u09aa\u09cd\u09b0\u09b6\u09cd\u09a8\u09aa\u09a4\u09cd\u09b0\u09c7\u09b0 \u09b8\u09c7\u099f\u09c7\u09b0 \u099c\u09a8\u09cd\u09af \u0986\u09ae\u09b0\u09be \u0985\u0982\u09b6\u0997\u09cd\u09b0\u09b9\u09a3\u0995\u09be\u09b0\u09c0\u09a6\u09c7\u09b0 \u09a4\u09be\u09a6\u09c7\u09b0 \u09b8\u09ae\u09af\u09bc\u09c7\u09b0 \u09ac\u09bf\u09a8\u09bf\u09ae\u09af\u09bc\u09c7 \u09e7\u09e6 \u09aa\u09be\u0989\u09a8\u09cd\u09a1 \u09aa\u09be\u09b0\u09bf\u09b6\u09cd\u09b0\u09ae\u09bf\u0995 \u09a6\u09c7\u09ac\u0964.<\/p>\n<p>\u0985\u09a8\u09c1\u09ae\u09a4\u09bf \u09b8\u09be\u09aa\u09c7\u0995\u09cd\u09b7\u09c7, \u0986\u09ae\u09b0\u09be \u09a4\u09be\u09a6\u09c7\u09b0 \u09b8\u09cd\u09ac\u09be\u09b8\u09cd\u09a5\u09cd\u09af \u09b8\u0982\u0995\u09cd\u09b0\u09be\u09a8\u09cd\u09a4 \u0985\u09cd\u09af\u09be\u09aa\u09af\u09bc\u09c7\u09a8\u09cd\u099f\u09ae\u09c7\u09a8\u09cd\u099f, \u09b9\u09be\u09b8\u09aa\u09be\u09a4\u09be\u09b2\u09c7 \u09ad\u09b0\u09cd\u09a4\u09bf \u098f\u09ac\u0982 \u09ac\u09c7\u0981\u099a\u09c7 \u09a5\u09be\u0995\u09be\u09b0 \u09b9\u09be\u09b0 \u09b8\u09ae\u09cd\u09aa\u09b0\u09cd\u0995\u09c7 \u099c\u09be\u09a8\u09a4\u09c7 \u09a4\u09be\u09a6\u09c7\u09b0 \u09ae\u09c7\u09a1\u09bf\u0995\u09c7\u09b2 \u09b0\u09c7\u0995\u09b0\u09cd\u09a1 \u09ac\u09cd\u09af\u09ac\u09b9\u09be\u09b0 \u0995\u09b0\u09ac\u0964 \u09b9\u09be\u09b0\u09cd\u099f \u09ab\u09c7\u0987\u09b2\u09bf\u0989\u09b0\u09c7 \u0986\u0995\u09cd\u09b0\u09be\u09a8\u09cd\u09a4 \u09ac\u09cd\u09af\u0995\u09cd\u09a4\u09bf\u09a6\u09c7\u09b0 \u099c\u09a8\u09cd\u09af \u0997\u09ac\u09c7\u09b7\u09a3\u09be\u09af\u09bc \u0985\u0982\u09b6\u0997\u09cd\u09b0\u09b9\u09a3 \u09b8\u09b9\u099c \u0995\u09b0\u09be\u09b0 \u0989\u09a6\u09cd\u09a6\u09c7\u09b6\u09cd\u09af\u09c7, \u0986\u09ae\u09b0\u09be \u0997\u09ac\u09c7\u09b7\u09a3\u09be\u09b0 \u0995\u09cb\u09a8\u09cb \u09ad\u09bf\u099c\u09bf\u099f\u09c7\u09b0 \u099c\u09a8\u09cd\u09af \u09a4\u09be\u09a6\u09c7\u09b0 \u09b9\u09be\u09b8\u09aa\u09be\u09a4\u09be\u09b2 \u09ac\u09be \u099c\u09bf\u09aa\u09bf \u09aa\u09cd\u09b0\u09cd\u09af\u09be\u0995\u099f\u09bf\u09b8\u09c7 \u0986\u09b8\u09a4\u09c7 \u09ac\u09b2\u09ac \u09a8\u09be\u0964.<\/p>\n<p>\u09a4\u09be\u09a6\u09c7\u09b0\u0995\u09c7 \u09a1\u09be\u0995\u09af\u09cb\u0997\u09c7 \u0997\u09ac\u09c7\u09b7\u09a3\u09be\u099f\u09bf \u09b8\u09ae\u09cd\u09aa\u09b0\u09cd\u0995\u09c7 \u09a4\u09a5\u09cd\u09af \u09aa\u09be\u09a0\u09be\u09a8\u09cb \u09b9\u09ac\u09c7, \u09a4\u09be\u09a6\u09c7\u09b0 \u099c\u09bf\u09aa\u09bf \u09ac\u09be \u09a8\u09be\u09b0\u09cd\u09b8 \u0997\u09ac\u09c7\u09b7\u09a3\u09be\u099f\u09bf \u09ac\u09cd\u09af\u09be\u0996\u09cd\u09af\u09be \u0995\u09b0\u09be\u09b0 \u099c\u09a8\u09cd\u09af \u09ab\u09cb\u09a8 \u0995\u09b0\u09ac\u09c7\u09a8 \u098f\u09ac\u0982 \u0997\u09ac\u09c7\u09b7\u09a3\u09be\u09b0 \u0994\u09b7\u09a7 \u09b8\u09b0\u09be\u09b8\u09b0\u09bf \u09a4\u09be\u09a6\u09c7\u09b0 \u09ac\u09be\u09a1\u09bc\u09bf\u09a4\u09c7 \u09aa\u09be\u09a0\u09bf\u09af\u09bc\u09c7 \u09a6\u09c7\u0993\u09af\u09bc\u09be \u09b9\u09ac\u09c7\u0964.<\/p>\n<p>\u0997\u09ac\u09c7\u09b7\u09a3\u09be\u09af\u09bc \u0985\u0982\u09b6\u0997\u09cd\u09b0\u09b9\u09a3\u0995\u09be\u09b0\u09c0 \u09ac\u09cd\u09af\u0995\u09cd\u09a4\u09bf\u09a6\u09c7\u09b0 \u09aa\u09cd\u09b0\u09b6\u09cd\u09a8\u09be\u09ac\u09b2\u09c0 \u09aa\u09c2\u09b0\u09a3 \u0995\u09b0\u09be\u09b0 \u099c\u09a8\u09cd\u09af \u09ac\u09bf\u09ad\u09bf\u09a8\u09cd\u09a8 \u09ac\u09bf\u0995\u09b2\u09cd\u09aa \u09a5\u09be\u0995\u09ac\u09c7: \u0985\u09a8\u09b2\u09be\u0987\u09a8\u09c7, \u099f\u09c7\u09b2\u09bf\u09ab\u09cb\u09a8\u09c7 \u0985\u09a5\u09ac\u09be \u09a4\u09be\u09a6\u09c7\u09b0 \u099c\u09bf\u09aa\u09bf \u09aa\u09cd\u09b0\u09cd\u09af\u09be\u0995\u099f\u09bf\u09b8\u09c7 \u09b8\u09b0\u09be\u09b8\u09b0\u09bf\u0964.<\/p>\n<h2>\u0997\u09ac\u09c7\u09b7\u09a3\u09be\u09b0 \u09a8\u09c7\u09a4\u09c3\u09a4\u09cd\u09ac \u0995\u09c7 \u09a6\u09bf\u099a\u09cd\u099b\u09c7\u09a8?<\/h2>\n<p><a href=\"https:\/\/www.bristol.ac.uk\/people\/person\/Maria-Pufulete-6812e04e-f4da-448d-91db-032c4eddd93a\/\" rel=\"noopener\">\u09a1\u0983 \u09ae\u09be\u09b0\u09bf\u09af\u09bc\u09be \u09aa\u09c1\u09ab\u09c1\u09b2\u09c7\u099f\u09c7<\/a>, \u09b8\u09bf\u09a8\u09bf\u09af\u09bc\u09b0 \u09b0\u09bf\u09b8\u09be\u09b0\u09cd\u099a \u09ab\u09c7\u09b2\u09cb, \u09ac\u09cd\u09b0\u09bf\u09b8\u09cd\u099f\u09b2 \u09ac\u09bf\u09b6\u09cd\u09ac\u09ac\u09bf\u09a6\u09cd\u09af\u09be\u09b2\u09af\u09bc \u098f\u09ac\u0982 <a href=\"https:\/\/www.bristol.ac.uk\/people\/person\/Rachel-Johnson-76214692-715a-441e-b67a-cfd9acdfa97a\/\" rel=\"noopener\">\u09a1\u0983 \u09b0\u200d\u09cd\u09af\u09be\u099a\u09c7\u09b2 \u099c\u09a8\u09b8\u09a8<\/a>, \u09aa\u09cd\u09b0\u09be\u09a5\u09ae\u09bf\u0995 \u09aa\u09b0\u09bf\u099a\u09b0\u09cd\u09af\u09be \u09ac\u09bf\u09ad\u09be\u0997\u09c7\u09b0 \u09b8\u09b9\u09af\u09cb\u0997\u09c0 \u0985\u09a7\u09cd\u09af\u09be\u09aa\u0995, \u09ac\u09cd\u09b0\u09bf\u09b8\u09cd\u099f\u09b2 \u09ac\u09bf\u09b6\u09cd\u09ac\u09ac\u09bf\u09a6\u09cd\u09af\u09be\u09b2\u09af\u09bc\u0964.<\/p>\n<h2>\u0986\u09b0\u0993 \u09a4\u09a5\u09cd\u09af:<\/h2>\n<p>\u0986\u09b0\u0993 \u09a4\u09a5\u09cd\u09af\u09c7\u09b0 \u099c\u09a8\u09cd\u09af \u0985\u09a5\u09ac\u09be \u098f\u0987 \u09aa\u09cd\u09b0\u0995\u09b2\u09cd\u09aa\u09c7 \u099c\u09a1\u09bc\u09bf\u09a4 \u09b9\u09a4\u09c7, \u0987\u09ae\u09c7\u09b2 \u0995\u09b0\u09c1\u09a8 <a href=\"mailto:bnssg.research@nhs.net\" target=\"_blank\" rel=\"noopener\">bnssg.research@nhs.net<\/a>.<\/p>\n<p>\u09aa\u09cd\u09b0\u0995\u09be\u09b6\u09bf\u09a4 \u09ae\u09a4\u09be\u09ae\u09a4 \u09b2\u09c7\u0996\u0995(\u09a6\u09c7\u09b0) \u09a8\u09bf\u099c\u09b8\u09cd\u09ac \u098f\u09ac\u0982 \u0985\u0997\u09a4\u09cd\u09af\u09be NIHR \u09ac\u09be \u09b8\u09cd\u09ac\u09be\u09b8\u09cd\u09a5\u09cd\u09af \u0993 \u09b8\u09ae\u09be\u099c\u09b8\u09c7\u09ac\u09be \u09ac\u09bf\u09ad\u09be\u0997\u09c7\u09b0 \u09ae\u09a4\u09be\u09ae\u09a4 \u09a8\u09af\u09bc\u0964.<\/p>\n  <\/div>\r\n  <\/section><\/div><!-- .assembler_text-module.assembler_module.assembler_text-module_1.assembler_module_1..transparent --><\/div><!-- .assembler_module_area.assembler_module_area_1 --><\/div><!-- .assembler_default-group.assembler_module_group.assembler_default-group_1.assembler_module_group_1  -->","protected":false},"excerpt":{"rendered":"<p>Section titled module-1 The effectiveness and cost effectiveness of coenzyme Q10 in heart failure with reduced ejection fraction: a pragmatic, patient-centred, data-enabled trial in primary care (CORAL) &nbsp; Funding National Institute for Health and Care Research (NIHR) Health Technology Assessment (HTA) Ref. NIHR152257. What is the problem? Heart failure means the heart can\u2019t pump blood [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":32881,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"tags":[],"class_list":["post-34548","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/bn\/wp-json\/wp\/v2\/pages\/34548","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/bn\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/bn\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/bn\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/bn\/wp-json\/wp\/v2\/comments?post=34548"}],"version-history":[{"count":3,"href":"https:\/\/bnssghealthiertogether.org.uk\/bn\/wp-json\/wp\/v2\/pages\/34548\/revisions"}],"predecessor-version":[{"id":36179,"href":"https:\/\/bnssghealthiertogether.org.uk\/bn\/wp-json\/wp\/v2\/pages\/34548\/revisions\/36179"}],"up":[{"embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/bn\/wp-json\/wp\/v2\/pages\/32881"}],"wp:attachment":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/bn\/wp-json\/wp\/v2\/media?parent=34548"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/bn\/wp-json\/wp\/v2\/tags?post=34548"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}