{"id":34498,"date":"2024-11-26T16:39:19","date_gmt":"2024-11-26T16:39:19","guid":{"rendered":"https:\/\/bnssghealthiertogether.org.uk\/?page_id=34498"},"modified":"2025-01-16T21:51:35","modified_gmt":"2025-01-16T21:51:35","slug":"improving-primary-care-antibiotic-prescribing-to-reduce-antibiotic-resistant-urine-infections-the-ipap-uti-programme","status":"publish","type":"page","link":"https:\/\/bnssghealthiertogether.org.uk\/ro\/integrated-care-board\/research-and-evidence\/our-research-portfolio\/nihr-funded-projects\/improving-primary-care-antibiotic-prescribing-to-reduce-antibiotic-resistant-urine-infections-the-ipap-uti-programme\/","title":{"rendered":"\u00cembun\u0103t\u0103\u021birea prescrierii antibioticelor \u00een asisten\u021ba medical\u0103 primar\u0103 pentru reducerea infec\u021biilor urinare rezistente la antibiotice: programul IPAP-UTI"},"content":{"rendered":"
Sec\u021biunea intitulat\u0103 modul-1<\/span><\/a>
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\u00cembun\u0103t\u0103\u021birea prescrierii antibioticelor \u00een asisten\u021ba medical\u0103 primar\u0103 pentru reducerea infec\u021biilor urinare rezistente la antibiotice: programul IPAP-UTI.<\/h1>\n
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<\/h2>\n

Finan\u021bare<\/h2>\n<\/article>\n

Institutul Na\u021bional pentru Cercetare \u00een S\u0103n\u0103tate \u0219i \u00cengrijire (NIHR) - Program de Granturi pentru Cercetare Aplicat\u0103 (PGfAR) - Ref. NIHR204400.<\/p>\n

Care este problema?<\/h2>\n

AMR este o amenin\u021bare serioas\u0103 la adresa s\u0103n\u0103t\u0103\u021bii. Dac\u0103 nu facem nimic, bacteriile vor deveni rezistente la tot mai multe antibiotice, p\u00e2n\u0103 c\u00e2nd infec\u021biile vor deveni netratabile. P\u00e2n\u0103 \u00een 2050, unii oameni de \u0219tiin\u021b\u0103 prev\u0103d c\u0103 mai mul\u021bi oameni vor muri din cauza infec\u021biilor cu AMR dec\u00e2t din cauza cancerului.<\/p>\n

ITU-urile sunt cele mai frecvente infec\u021bii bacteriene tratate \u00een NHS, \u00een mare parte folosind antibiotice prescrise de medicii generali\u0219ti (GP) \u0219i asistentele medicale din asisten\u021ba medical\u0103 primar\u0103.<\/p>\n

P\u00e2n\u0103 la 50% de bacterii care cauzeaz\u0103 infec\u021bii ale tractului urinar sunt rezistente la cel pu\u021bin un antibiotic, ceea ce \u00eenseamn\u0103 c\u0103 antibioticul respectiv nu mai este un tratament eficient. Aceasta \u00eenseamn\u0103 c\u0103 oamenii pot avea infec\u021bii mai lungi \u0219i mai severe \u0219i pot avea nevoie de mai multe cure de antibiotice.<\/p>\n

Medicii de familie \u0219i asistentele medicale au fost \u00eencuraja\u021bi s\u0103 prescrie nitrofurantoin\u0103 \u00een loc de trimetoprim (ambele fiind antibiotice de prim\u0103 licen\u021b\u0103 pentru infec\u021biile urinare). Unele studii sugereaz\u0103 c\u0103 acest lucru a redus ratele de rezisten\u021b\u0103 la AMR cauzate de trimetoprim, dar ar fi putut duce la rate mai mari de rezisten\u021b\u0103 la AMR pentru alte antibiotice.<\/p>\n

Aceste rezultate \u00eei determin\u0103 pe factorii de decizie s\u0103 pun\u0103 dou\u0103 \u00eentreb\u0103ri. Prima: \u2018Sunt aceste rezultate fiabile?\u2019 \u0219i a doua: \u2018Ce ar trebui f\u0103cut?\u2019<\/p>\n

Ca r\u0103spuns, datele nu sunt fiabile deoarece metodele utilizate \u00eenseamn\u0103 c\u0103 ar putea exista \u0219i alte motive pentru schimb\u0103ri \u0219i nimeni nu \u0219tie ce s\u0103 fac\u0103 \u00een continuare. Exist\u0103 idei, dar nu \u0219tim dac\u0103 beneficiile dep\u0103\u0219esc daunele.<\/p>\n

Care este scopul cercet\u0103rii?<\/h2>\n

Ne propunem s\u0103 acumul\u0103m dovezi fiabile care s\u0103 ajute medicii s\u0103 aleag\u0103 cel mai bun antibiotic pentru tratarea infec\u021biilor tractului urinar (ITU) \u00een asisten\u021ba medical\u0103 primar\u0103, pentru a reduce rezisten\u021ba la antibiotice (antimicrobiene) (AMR).<\/p>\n

Cum se va realiza acest lucru?<\/h2>\n

Un studiu clinic randomizat controlat (RCT) este singura metod\u0103 fiabil\u0103 de investigare a eficacit\u0103\u021bii medicamentelor. Acest program va include trei RCT-uri care vor fi efectuate \u00een zone cu probleme severe de rezisten\u021b\u0103 antimicrobic\u0103 \u0219i \u00een grupurile cele mai afectate. Se va raporta dac\u0103 rasa, v\u00e2rsta sau situa\u021bia financiar\u0103 afecteaz\u0103 rezultatele.<\/p>\n

Unele cabinete medicale de familie vor fi \u00eencurajate s\u0103 utilizeze un antibiotic alternativ (sau s\u0103 combine dou\u0103 antibiotice), iar celelalte vor continua tratamentul obi\u0219nuit. Vom compara utilizarea antibioticelor \u0219i ratele de rezisten\u021b\u0103 la antibiotice (AMR) \u0219i ne a\u0219tept\u0103m ca orice diferen\u021be s\u0103 se datoreze interven\u021biei.<\/p>\n

Cine conduce cercetarea?<\/h2>\n

Profesorul Alastair D. Hay<\/a>, Profesor de asisten\u021b\u0103 medical\u0103 primar\u0103, Universitatea din Bristol.<\/p>\n

Informa\u021bii suplimentare:<\/h2>\n

Pentru mai multe informa\u021bii sau pentru a v\u0103 implica \u00een acest proiect, trimite\u021bi un e-mail la bnssg.research@nhs.net<\/a>.<\/p>\n

Opiniile exprimate sunt cele ale autorului (autorilor) \u0219i nu neap\u0103rat cele ale NIHR sau ale Departamentului de S\u0103n\u0103tate \u0219i Asisten\u021b\u0103 Social\u0103.<\/p>\n <\/div>\r\n <\/section><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"

Section titled module-1 Improving primary care antibiotic prescribing to reduce antibiotic resistant urine infections: the IPAP-UTI programme. Funding National Institute for Health and Care Research (NIHR) Programme Grants for Applied Research (PGfAR) Ref. NIHR204400. What is the problem? AMR is a serious threat to health. Unless we do something, bacteria will become resistant to more […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":32881,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"tags":[],"class_list":["post-34498","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/ro\/wp-json\/wp\/v2\/pages\/34498","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/ro\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/ro\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/ro\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/ro\/wp-json\/wp\/v2\/comments?post=34498"}],"version-history":[{"count":3,"href":"https:\/\/bnssghealthiertogether.org.uk\/ro\/wp-json\/wp\/v2\/pages\/34498\/revisions"}],"predecessor-version":[{"id":36160,"href":"https:\/\/bnssghealthiertogether.org.uk\/ro\/wp-json\/wp\/v2\/pages\/34498\/revisions\/36160"}],"up":[{"embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/ro\/wp-json\/wp\/v2\/pages\/32881"}],"wp:attachment":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/ro\/wp-json\/wp\/v2\/media?parent=34498"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/ro\/wp-json\/wp\/v2\/tags?post=34498"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}