{"id":34476,"date":"2024-11-26T16:35:45","date_gmt":"2024-11-26T16:35:45","guid":{"rendered":"https:\/\/bnssghealthiertogether.org.uk\/?page_id=34476"},"modified":"2025-01-16T10:25:46","modified_gmt":"2025-01-16T10:25:46","slug":"epitope-evaluating-the-population-impact-of-hepatitis-c-direct-acting-antiviral-treatment-as-prevention-for-people-who-inject-drugs","status":"publish","type":"page","link":"https:\/\/bnssghealthiertogether.org.uk\/sq\/integrated-care-board\/research-and-evidence\/our-research-portfolio\/nihr-funded-projects\/epitope-evaluating-the-population-impact-of-hepatitis-c-direct-acting-antiviral-treatment-as-prevention-for-people-who-inject-drugs\/","title":{"rendered":"EPIToPe: Vler\u00ebsimi i ndikimit n\u00eb popullsi t\u00eb trajtimit antiviral me veprim t\u00eb drejtp\u00ebrdrejt\u00eb t\u00eb hepatitit C si parandalim p\u00ebr njer\u00ebzit q\u00eb injektojn\u00eb drog\u00eb"},"content":{"rendered":"
Seksioni me titull module-1<\/span><\/a>
\r\n
\r\n
\n
\n

EPIToPe: Vler\u00ebsimi i ndikimit n\u00eb popullsi t\u00eb trajtimit antiviral me veprim t\u00eb drejtp\u00ebrdrejt\u00eb t\u00eb hepatitit C si parandalim p\u00ebr njer\u00ebzit q\u00eb injektojn\u00eb drog\u00eb<\/h1>\n<\/div>\n<\/header>\n
\n

<\/h2>\n

Financimi<\/h2>\n<\/article>\n

Programi i Granteve p\u00ebr K\u00ebrkime t\u00eb Aplikuara t\u00eb Institutit Komb\u00ebtar t\u00eb Sh\u00ebndet\u00ebsis\u00eb (NIHR) (PGfAR) Ref. RP-PG-0616-20008<\/p>\n

Cila \u00ebsht\u00eb pyetja k\u00ebrkimore?<\/h2>\n

A e zvog\u00eblon p\u00ebrshkall\u00ebzimi i trajtimit t\u00eb Virusit t\u00eb Hepatitit C (HCV) tek Personat q\u00eb Injektojn\u00eb Droga (PWID) prevalenc\u00ebn dhe transmetimin e HCV n\u00eb popullat\u00eb?<\/p>\n

Cili \u00ebsht\u00eb problemi?<\/h2>\n

Rreth 200,000 njer\u00ebz n\u00eb Mbret\u00ebrin\u00eb e Bashkuar jan\u00eb infektuar me virusin e hepatitit C (HCV), i cili \u00ebsht\u00eb nj\u00eb shkak i r\u00ebnd\u00ebsish\u00ebm i s\u00ebmundjeve t\u00eb m\u00ebl\u00e7is\u00eb, kancerit dhe vdekjes.<\/p>\n

Shumica e infeksioneve t\u00eb HCV n\u00eb Mbret\u00ebrin\u00eb e Bashkuar ndodhin tek njer\u00ebzit q\u00eb injektojn\u00eb drog\u00eb. Barnat e reja t\u00eb HCV sh\u00ebrojn\u00eb mbi 90% pacient\u00eb brenda 12 jav\u00ebsh me pak efekte an\u00ebsore, por jan\u00eb t\u00eb shtrenjta (mbi 20,000 \u00a3) dhe aktualisht t\u00eb kufizuara p\u00ebr njer\u00ebzit me s\u00ebmundje t\u00eb moderuar ose t\u00eb r\u00ebnd\u00eb t\u00eb m\u00ebl\u00e7is\u00eb.<\/p>\n

Modelet matematikore sugjerojn\u00eb q\u00eb \u201cTrajtimi si Parandalim\u201d i HCV-s\u00eb, pra trajtimi i njer\u00ebzve q\u00eb injektojn\u00eb droga dhe kan\u00eb s\u00ebmundje t\u00eb leht\u00eb t\u00eb m\u00ebl\u00e7is\u00eb p\u00ebr HCV-n\u00eb, mund t\u00eb zvog\u00ebloj\u00eb numrin e p\u00ebrgjithsh\u00ebm t\u00eb infeksioneve t\u00eb reja me HCV n\u00eb popullat\u00eb, edhe pse disa njer\u00ebz q\u00eb injektojn\u00eb droga mund t\u00eb ri-infektohen.<\/p>\n

P\u00ebr m\u00eb tep\u00ebr, n\u00ebse trajtimi i HCV rritet mjaftuesh\u00ebm, HCV p\u00ebrfundimisht do t\u00eb "eliminohet" nga popullata e Mbret\u00ebris\u00eb s\u00eb Bashkuar. Gjetjet nga k\u00ebto modele duhet t\u00eb testohen te pacient\u00ebt.<\/p>\n

Cili \u00ebsht\u00eb q\u00ebllimi i hulumtimit?<\/h2>\n

Gjetjet nga k\u00ebto modele t\u00eb HCV duhet t\u00eb testohen te pacient\u00ebt. Ky studim do t\u00eb hetoj\u00eb n\u00ebse trajtimi i personave q\u00eb injektojn\u00eb drog\u00eb dhe kan\u00eb s\u00ebmundje t\u00eb leht\u00eb t\u00eb m\u00ebl\u00e7is\u00eb p\u00ebr HCV mund ta zvog\u00ebloj\u00eb HCV n\u00eb k\u00ebt\u00eb popullat\u00eb.<\/p>\n

Si do t\u00eb arrihet kjo?<\/h2>\n

N\u00eb studimin e par\u00eb, synojm\u00eb t\u00eb trajtojm\u00eb t\u00eb pakt\u00ebn 500 persona q\u00eb injektojn\u00eb drog\u00eb n\u00eb Dundee\/NHS Tayside gjat\u00eb dy viteve. Kjo rritje e madhe dhe e shpejt\u00eb e trajtimit t\u00eb HCV do t\u00eb ofrohet n\u00eb vende t\u00eb shumta n\u00eb komunitet, duke p\u00ebrfshir\u00eb farmacit\u00eb, sh\u00ebrbimet e var\u00ebsis\u00eb dhe burgjet.<\/p>\n

Ne vler\u00ebsojm\u00eb se kjo do ta zvog\u00ebloj\u00eb HCV kronik tek njer\u00ebzit q\u00eb injektojn\u00eb droga n\u00eb Dundee me dy t\u00eb tretat, nga gati 30% n\u00eb m\u00eb pak se 10%.<\/p>\n

P\u00ebr t\u00eb matur ndryshimet n\u00eb HCV n\u00eb popullat\u00eb, duhet t\u00eb rrisim t\u00eb dh\u00ebnat e disponueshme nga anketat e njer\u00ebzve q\u00eb injektojn\u00eb droga n\u00eb Tayside dhe pjes\u00ebn tjet\u00ebr t\u00eb Mbret\u00ebris\u00eb s\u00eb Bashkuar dhe t\u00eb zhvillojm\u00eb metoda t\u00eb reja statistikore q\u00eb mund t\u00eb ofrojn\u00eb vler\u00ebsime t\u00eb paanshme n\u00ebse HCV ka ndryshuar me kalimin e koh\u00ebs.<\/p>\n

Ne do t\u00eb intervistojm\u00eb ofruesit e sh\u00ebrbimeve n\u00eb Dundee\/NHS Tayside p\u00ebr t\u00eb identifikuar pengesat dhe leht\u00ebsuesit kryesor\u00eb q\u00eb mund t\u00eb ndihmojn\u00eb vendet e tjera t\u00eb rrisin me sukses trajtimin e HCV.<\/p>\n

Ne do t\u00eb intervistojm\u00eb pacient\u00ebt pas trajtimit dhe do t\u00eb krijojm\u00eb lidhje me bazat e t\u00eb dh\u00ebnave administrative p\u00ebr t\u00eb vler\u00ebsuar n\u00ebse sh\u00ebrimi nga HCV i ndihmon gjithashtu njer\u00ebzit q\u00eb injektojn\u00eb drog\u00eb t\u00eb q\u00ebndrojn\u00eb n\u00eb trajtimin e specializuar t\u00eb drog\u00ebs dhe t\u00eb sh\u00ebrohen nga var\u00ebsia. Gjithashtu do t\u00eb vler\u00ebsojm\u00eb n\u00ebse rritja e trajtimit t\u00eb HCV p\u00ebr njer\u00ebzit q\u00eb injektojn\u00eb drog\u00eb \u00ebsht\u00eb me kosto efektive p\u00ebr NHS-n\u00eb.<\/p>\n

S\u00eb fundmi, nd\u00ebrsa trajtimet e HCV rriten n\u00eb Angli, ne do t\u00eb hartojm\u00eb s\u00eb bashku nj\u00eb vler\u00ebsim t\u00eb dyt\u00eb dhe m\u00eb t\u00eb gjer\u00eb t\u00eb "Trajtimit si Parandalim" t\u00eb HCV me sh\u00ebrbimet klinike rajonale t\u00eb HCV. Ne do t\u00eb p\u00ebrdorim prova nga studimi yn\u00eb i par\u00eb p\u00ebr t\u00eb treguar se si mund ta shkall\u00ebzojm\u00eb trajtimin e HCV n\u00eb komunitet dhe p\u00ebr t\u00eb p\u00ebrcaktuar n\u00ebse infeksionet e HCV zvog\u00eblohen m\u00eb shum\u00eb n\u00eb vendet me shkall\u00ebzim m\u00eb t\u00eb madh sesa n\u00eb vendet me shkall\u00ebzim m\u00eb pak intensiv t\u00eb trajtimit t\u00eb HCV.<\/p>\n

Kush po e udh\u00ebheq hulumtimin?<\/h2>\n

Prof. Matt Hickman, Profesor n\u00eb Sh\u00ebndetin Publik dhe Epidemiologjin\u00eb, Shkencat e Sh\u00ebndetit t\u00eb Popullsis\u00eb, Universiteti i Bristolit.<\/p>\n

Informacione t\u00eb m\u00ebtejshme:<\/h2>\n

Rreth EPITOPE<\/a><\/p>\n

P\u00ebr m\u00eb shum\u00eb informacion ose p\u00ebr t'u p\u00ebrfshir\u00eb n\u00eb k\u00ebt\u00eb projekt, d\u00ebrgoni email bnssg.research@nhs.net<\/a>.<\/p>\n

Pik\u00ebpamjet e shprehura jan\u00eb ato t\u00eb autorit\/autor\u00ebve dhe jo domosdoshm\u00ebrisht ato t\u00eb NIHR ose t\u00eb Departamentit t\u00eb Sh\u00ebndet\u00ebsis\u00eb dhe Kujdesit Social.<\/p>\n <\/div>\r\n <\/section><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"

Section titled module-1 EPIToPe: Evaluating the Population Impact of Hepatitis C Direct Acting Antiviral Treatment as Prevention for People Who Inject Drugs Funding National Institute for Health (NIHR) Programme Grants for Applied Research (PGfAR) Ref. RP-PG-0616-20008 What is the research question? Does scaling-up Hepatitis C Virus (HCV) treatment among People Who Inject Drugs (PWID) reduce […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":32881,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"tags":[],"class_list":["post-34476","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/pages\/34476","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/comments?post=34476"}],"version-history":[{"count":4,"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/pages\/34476\/revisions"}],"predecessor-version":[{"id":36109,"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/pages\/34476\/revisions\/36109"}],"up":[{"embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/pages\/32881"}],"wp:attachment":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/media?parent=34476"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/tags?post=34476"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}