{"id":34548,"date":"2024-11-26T16:46:57","date_gmt":"2024-11-26T16:46:57","guid":{"rendered":"https:\/\/bnssghealthiertogether.org.uk\/?page_id=34548"},"modified":"2025-01-16T22:41:05","modified_gmt":"2025-01-16T22:41:05","slug":"the-effectiveness-and-cost-effectiveness-of-coenzyme-q10-in-heart-failure-with-reduced-ejection-fraction-a-pragmatic-patient-centred-data-enabled-trial-in-primary-care-coral","status":"publish","type":"page","link":"https:\/\/bnssghealthiertogether.org.uk\/sq\/integrated-care-board\/research-and-evidence\/our-research-portfolio\/nihr-funded-projects\/the-effectiveness-and-cost-effectiveness-of-coenzyme-q10-in-heart-failure-with-reduced-ejection-fraction-a-pragmatic-patient-centred-data-enabled-trial-in-primary-care-coral\/","title":{"rendered":"Efektiviteti dhe efektiviteti i kostos s\u00eb koenzim\u00ebs Q10 n\u00eb d\u00ebshtimin e zemr\u00ebs me fraksion t\u00eb reduktuar t\u00eb ejeksionit: nj\u00eb prov\u00eb pragmatike, e p\u00ebrqendruar te pacienti dhe e mund\u00ebsuar nga t\u00eb dh\u00ebnat n\u00eb kujdesin par\u00ebsor (CORAL)"},"content":{"rendered":"
Seksioni me titull module-1<\/span><\/a>
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Efektiviteti dhe efektiviteti i kostos s\u00eb koenzim\u00ebs Q10 n\u00eb d\u00ebshtimin e zemr\u00ebs me ulje t\u00eb
\nfraksioni i nxjerrjes: nj\u00eb prov\u00eb pragmatike, e p\u00ebrqendruar te pacienti dhe e bazuar n\u00eb t\u00eb dh\u00ebna n\u00eb kujdesin par\u00ebsor (CORAL)<\/h1>\n

 <\/p>\n

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Financimi<\/h2>\n<\/article>\n

Instituti Komb\u00ebtar p\u00ebr K\u00ebrkime n\u00eb Sh\u00ebndet\u00ebsi dhe Kujdes (NIHR) Vler\u00ebsimi i Teknologjis\u00eb Sh\u00ebndet\u00ebsore (HTA) Ref. NIHR152257.<\/p>\n

Cili \u00ebsht\u00eb problemi?<\/h2>\n

D\u00ebshtimi i zemr\u00ebs do t\u00eb thot\u00eb q\u00eb zemra nuk mund t\u00eb pompoj\u00eb gjakun si\u00e7 duhet, qoft\u00eb sepse \u00ebsht\u00eb shum\u00eb e dob\u00ebt ose shum\u00eb e ngurt\u00eb. Njer\u00ebzit me d\u00ebshtim t\u00eb zemr\u00ebs shpesh ndihen t\u00eb lodhur dhe t\u00eb pafuqish\u00ebm. K\u00ebmb\u00ebt dhe ky\u00e7et e k\u00ebmb\u00ebve u \u00ebnjten. K\u00ebto simptoma mund t\u00eb \u00e7ojn\u00eb n\u00eb cil\u00ebsi t\u00eb dob\u00ebt t\u00eb jet\u00ebs.<\/p>\n

Njer\u00ebzit me pamjaftueshm\u00ebri kardiake dhe profesionist\u00ebt e tyre t\u00eb sh\u00ebndetit thon\u00eb se k\u00ebrkimet p\u00ebr t\u00eb kuptuar se \u00e7far\u00eb mund t\u00eb p\u00ebrmir\u00ebsoj\u00eb cil\u00ebsin\u00eb e jet\u00ebs jan\u00eb m\u00eb t\u00eb r\u00ebnd\u00ebsishme p\u00ebr ta.<\/p>\n

D\u00ebshtimi i zemr\u00ebs diagnostikohet duke p\u00ebrdorur nj\u00eb skanim t\u00eb zemr\u00ebs (nj\u00eb ekokardiogram\u00eb). Kjo mat "fraksionin e nxjerrjes" - sasin\u00eb e gjakut q\u00eb shtrydhet nga dhoma kryesore pompuese e zemr\u00ebs me \u00e7do rrahje zemre.<\/p>\n

Disa njer\u00ebz me pamjaftueshm\u00ebri kardiake kan\u00eb nj\u00eb fraksion t\u00eb ejeksionit normal, por ky hulumtim p\u00ebrqendrohet te njer\u00ebzit me pamjaftueshm\u00ebri kardiake me nj\u00eb fraksion t\u00eb ejeksionit t\u00eb reduktuar.<\/p>\n

Cili \u00ebsht\u00eb q\u00ebllimi i hulumtimit?<\/h2>\n

Q\u00ebllimi kryesor i studimit \u00ebsht\u00eb t\u00eb zbuloj\u00eb n\u00ebse koenzima Q10 p\u00ebrmir\u00ebson cil\u00ebsin\u00eb e jet\u00ebs. Koenzima Q10 \u00ebsht\u00eb nj\u00eb substanc\u00eb e ngjashme me vitamin\u00ebn q\u00eb gjendet natyrsh\u00ebm n\u00eb trup dhe n\u00eb disa ushqime.<\/p>\n

Ne duam t\u00eb kryejm\u00eb nj\u00eb studim p\u00ebr t\u00eb zbuluar n\u00ebse marrja e koenzim\u00ebs Q10 \u00ebsht\u00eb e dobishme p\u00ebr njer\u00ebzit me pamjaftueshm\u00ebri kardiake dhe fraksion t\u00eb reduktuar t\u00eb ejeksionit.<\/p>\n

Si do t\u00eb arrihet kjo?<\/h2>\n

Do ta zbulojm\u00eb k\u00ebt\u00eb duke u k\u00ebrkuar njer\u00ebzve q\u00eb marrin pjes\u00eb t\u00eb plot\u00ebsojn\u00eb pyet\u00ebsor\u00ebt. Pyet\u00ebsor\u00ebt do t\u00eb pyesin p\u00ebr cil\u00ebsin\u00eb e jet\u00ebs s\u00eb tyre dhe jet\u00ebn e p\u00ebrditshme (Pyet\u00ebsori i Kardiomiopatis\u00eb s\u00eb Kansas City-t, pyet\u00ebsori i EuroQol 5 Dimensions of health dhe pyet\u00ebsori i Shoqat\u00ebs s\u00eb Zemr\u00ebs s\u00eb Nju Jorkut).<\/p>\n

Gjithashtu, do t\u00eb ket\u00eb nj\u00eb pyet\u00ebsor q\u00eb do t\u00eb pyes\u00eb se si pamjaftueshm\u00ebria e zemr\u00ebs ndikon financiarisht tek ata dhe kujdestar\u00ebt e tyre. Personave q\u00eb marrin pjes\u00eb n\u00eb studim do t'u k\u00ebrkohet t\u00eb plot\u00ebsojn\u00eb k\u00ebta pyet\u00ebsor\u00eb para se t\u00eb filloj\u00eb studimi, pastaj n\u00eb 3, 6, 9 muaj dhe nj\u00eb vit (kur studimi p\u00ebrfundon).<\/p>\n

Ne mendojm\u00eb se plot\u00ebsimi i pyet\u00ebsor\u00ebve do t\u00eb zgjas\u00eb rreth 35 minuta dhe ne do t'i kompensojm\u00eb njer\u00ebzit me 10 \u00a3 p\u00ebr koh\u00ebn e tyre p\u00ebr secilin grup pyet\u00ebsor\u00ebsh.<\/p>\n

Me leje, ne do t\u00eb p\u00ebrdorim kartel\u00ebn e tyre mjek\u00ebsore p\u00ebr t\u00eb m\u00ebsuar rreth takimeve sh\u00ebndet\u00ebsore, shtrimeve n\u00eb spital dhe mbijetes\u00ebs. P\u00ebr ta b\u00ebr\u00eb t\u00eb leht\u00eb p\u00ebr njer\u00ebzit me pamjaftueshm\u00ebri kardiake t\u00eb marrin pjes\u00eb n\u00eb studim, ne nuk do t'u k\u00ebrkojm\u00eb atyre t\u00eb paraqiten n\u00eb spital ose n\u00eb praktik\u00ebn e mjekut t\u00eb tyre t\u00eb familjes p\u00ebr asnj\u00eb vizit\u00eb studimore.<\/p>\n

Atyre do t'u d\u00ebrgohet informacion n\u00eb lidhje me studimin me post\u00eb, mjeku i tyre i familjes ose infermierja do t'i telefonoj\u00eb p\u00ebr t'u shpjeguar studimin dhe ila\u00e7et e tyre t\u00eb studimit do t'u d\u00ebrgohen direkt n\u00eb sht\u00ebpin\u00eb e tyre.<\/p>\n

Personat q\u00eb marrin pjes\u00eb n\u00eb studim do t\u00eb ken\u00eb disa mund\u00ebsi p\u00ebr plot\u00ebsimin e pyet\u00ebsor\u00ebve t\u00eb tyre: n\u00eb internet, me telefon ose ball\u00eb p\u00ebr ball\u00eb n\u00eb praktik\u00ebn e mjekut t\u00eb tyre t\u00eb p\u00ebrgjithsh\u00ebm.<\/p>\n

Kush po e udh\u00ebheq hulumtimin?<\/h2>\n

Dr. Maria Pufulete<\/a>, Bashk\u00ebpun\u00ebtor i Lart\u00eb K\u00ebrkimor, Universiteti i Bristolit dhe Dr. Rachel Johnson<\/a>, Profesor i Asociuar n\u00eb Kujdesin Par\u00ebsor, Universiteti i Bristolit.<\/p>\n

Informacione t\u00eb m\u00ebtejshme:<\/h2>\n

P\u00ebr m\u00eb shum\u00eb informacion ose p\u00ebr t'u p\u00ebrfshir\u00eb n\u00eb k\u00ebt\u00eb projekt, d\u00ebrgoni email bnssg.research@nhs.net<\/a>.<\/p>\n

Pik\u00ebpamjet e shprehura jan\u00eb ato t\u00eb autorit\/autor\u00ebve dhe jo domosdoshm\u00ebrisht ato t\u00eb NIHR ose t\u00eb Departamentit t\u00eb Sh\u00ebndet\u00ebsis\u00eb dhe Kujdesit Social.<\/p>\n <\/div>\r\n <\/section><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"

Section titled module-1 The effectiveness and cost effectiveness of coenzyme Q10 in heart failure with reduced ejection fraction: a pragmatic, patient-centred, data-enabled trial in primary care (CORAL)   Funding National Institute for Health and Care Research (NIHR) Health Technology Assessment (HTA) Ref. NIHR152257. What is the problem? Heart failure means the heart can\u2019t pump blood […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":32881,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"tags":[],"class_list":["post-34548","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/pages\/34548","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/comments?post=34548"}],"version-history":[{"count":3,"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/pages\/34548\/revisions"}],"predecessor-version":[{"id":36179,"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/pages\/34548\/revisions\/36179"}],"up":[{"embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/pages\/32881"}],"wp:attachment":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/media?parent=34548"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/sq\/wp-json\/wp\/v2\/tags?post=34548"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}