{"id":34557,"date":"2024-11-26T16:48:11","date_gmt":"2024-11-26T16:48:11","guid":{"rendered":"https:\/\/bnssghealthiertogether.org.uk\/?page_id=34557"},"modified":"2025-01-16T22:47:20","modified_gmt":"2025-01-16T22:47:20","slug":"trial-of-ige-tests-for-eczema-relief-tiger","status":"publish","type":"page","link":"https:\/\/bnssghealthiertogether.org.uk\/tr\/integrated-care-board\/research-and-evidence\/our-research-portfolio\/nihr-funded-projects\/trial-of-ige-tests-for-eczema-relief-tiger\/","title":{"rendered":"Egzama Rahatlamas\u0131 i\u00e7in IGe testlerinin denemesi (TIGER)."},"content":{"rendered":"
Mod\u00fcl-1 ba\u015fl\u0131kl\u0131 b\u00f6l\u00fcm<\/span><\/a>
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Egzama Rahatlamas\u0131 i\u00e7in IGe testlerinin denemesi (TIGER).<\/h1>\n

 <\/p>\n

Finansman: <\/strong><\/h2>\n

Ulusal Sa\u011fl\u0131k ve Bak\u0131m Ara\u015ft\u0131rma Enstit\u00fcs\u00fc (NIHR), Sa\u011fl\u0131k Teknolojisi De\u011ferlendirmesi (HTA) Referans No: NIHR133464.<\/p>\n

Ara\u015ft\u0131rma sorusu nedir?<\/strong><\/h2>\n

Rutin g\u0131da alerjisi testlerine dayal\u0131 diyet \u00f6nerileri, egzama hastas\u0131 \u00e7ocuklarda ola\u011fan bak\u0131ma k\u0131yasla hastal\u0131\u011f\u0131n kontrol\u00fcn\u00fc iyile\u015ftirir mi?<\/p>\n

Sorun nedir?<\/strong><\/h2>\n

Egzama, \u00e7ocuklarda 1,5 ila oran\u0131nda g\u00f6r\u00fclen yayg\u0131n ve uzun s\u00fcreli bir rahats\u0131zl\u0131kt\u0131r ve bu rahats\u0131zl\u0131k hakk\u0131ndaki anlay\u0131\u015f\u0131m\u0131z geli\u015fmi\u015f olsa da, umut vadeden \u00f6nleme stratejileri hayal k\u0131r\u0131kl\u0131\u011f\u0131 yaratm\u0131\u015ft\u0131r.<\/p>\n

2013 K\u00fcresel Hastal\u0131k Y\u00fck\u00fc \u00c7al\u0131\u015fmas\u0131nda, egzama, n\u00fcfus d\u00fczeyinde en b\u00fcy\u00fck engellili\u011fe yol a\u00e7an cilt hastal\u0131\u011f\u0131 olarak belirlenmi\u015ftir. Etkisi okul \u00f6ncesi \u00e7ocuklarda g\u00f6r\u00fclmekte olup, etkilenen \u00e7ocu\u011fun ve ailesinin fiziksel, duygusal ve sosyal i\u015flevlerini \u00f6nemli \u00f6l\u00e7\u00fcde etkilemektedir.<\/p>\n

Birle\u015fik Krall\u0131k'ta egzama sorunu ya\u015fayan \u00e7ocuklar\u0131n \u00e7o\u011fu, g\u00fcnl\u00fck olarak kullan\u0131lan topikal tedavilerle kontrol alt\u0131na al\u0131nmaktad\u0131r. Tedaviye ba\u011fl\u0131 kalmak zor olabiliyor \u00e7\u00fcnk\u00fc bir\u00e7ok ebeveyn hastal\u0131\u011f\u0131 kontrol alt\u0131na almak yerine "neden" aray\u0131\u015f\u0131na giriyor.<\/p>\n

Bir\u00e7ok ebeveyn, \u00e7ocuklar\u0131n\u0131n s\u00fcrekli devam eden egzama semptomlar\u0131n\u0131n nedeninin te\u015fhis edilmemi\u015f bir g\u0131da alerjisi olmas\u0131ndan endi\u015fe duymaktad\u0131r. Erken ba\u015flang\u0131\u00e7l\u0131 ve \u015fiddetli egzamas\u0131 olan \u00e7ocuklar, ani g\u0131da alerjisi riski alt\u0131ndad\u0131r.<\/p>\n

Endi\u015fe verici olsa da, bu t\u00fcr bir reaksiyonu genellikle tan\u0131mak kolayd\u0131r ve neden olan yiyecekten ka\u00e7\u0131nmak i\u00e7in net y\u00f6nlendirmelerle y\u00f6netilebilir. Bununla birlikte, bir\u00e7ok ebeveyn olas\u0131 gecikmi\u015f reaksiyonlardan endi\u015fe duymaktad\u0131r. Bu durum, egzaman\u0131n iyile\u015fiyor gibi g\u00f6r\u00fcnmesine ra\u011fmen tekrarlamas\u0131 ve nedenini belirlemeyi zorla\u015ft\u0131rmas\u0131 nedeniyle daha da karma\u015f\u0131k hale gelmi\u015ftir.<\/p>\n

Ebeveynlerin, sa\u011fl\u0131k uzman\u0131yla g\u00f6r\u00fc\u015fmeden etkilenen \u00e7ocu\u011fun diyetini k\u0131s\u0131tlamalar\u0131 yayg\u0131n bir durumdur. Bu, yetersiz beslenmeye yol a\u00e7abilecek potansiyel olarak tehlikeli bir karard\u0131r.<\/p>\n

Egzama tedavisinde beslenmenin rol\u00fcn\u00fc doktorlar\u0131yla g\u00f6r\u00fc\u015fen ebeveynler, genellikle beslenme k\u0131s\u0131tlamalar\u0131na rehberlik etmesi i\u00e7in alerji testi yap\u0131lmas\u0131n\u0131 isterler. Bu durumda, g\u0131da alerjisi testine rehberlik edecek kan\u0131tlar zay\u0131ft\u0131r ve de\u011feri hakk\u0131ndaki g\u00f6r\u00fc\u015fler farkl\u0131l\u0131k g\u00f6stermektedir; bu da klinik uygulamada farkl\u0131l\u0131klara ve ebeveynler i\u00e7in kafa kar\u0131\u015f\u0131kl\u0131\u011f\u0131na yol a\u00e7maktad\u0131r.<\/p>\n

Esasen, ebeveynler \u00e7ocuklar\u0131n\u0131n egzamas\u0131na neden olacak bir \u015fey bulmak i\u00e7in genellikle g\u0131da alerjisi testleri veya k\u0131s\u0131tl\u0131 diyetler ararlar, ancak testlerle y\u00f6nlendirilen diyet tavsiyelerinin de\u011feri belirsizdir.<\/p>\n

Ara\u015ft\u0131rman\u0131n amac\u0131 nedir?<\/strong><\/h2>\n

Egzama tedavisinde test sonu\u00e7lar\u0131na dayal\u0131 diyet \u00f6nerilerinin, ola\u011fan bak\u0131ma k\u0131yasla klinik ve maliyet etkinli\u011fini belirlemek.<\/p>\n

Bu nas\u0131l ba\u015far\u0131lacak?<\/strong><\/h2>\n

Daha \u00f6nceki bir ara\u015ft\u0131rmada, yumurta alerjisi testi pozitif \u00e7\u0131kan egzamal\u0131 bebeklerin yumurtas\u0131z bir diyetten fayda g\u00f6rd\u00fc\u011f\u00fc \u00f6ne s\u00fcr\u00fclm\u00fc\u015ft\u00fc, ancak daha iyi tasarlanm\u0131\u015f bir \u00e7al\u0131\u015fmaya ihtiya\u00e7 var.<\/p>\n

Birinci basamak sa\u011fl\u0131k hizmetlerinde, "Besin alerjisi testlerine dayal\u0131 diyet \u00f6nerileri, egzamal\u0131 \u00e7ocuklarda hastal\u0131k kontrol\u00fcn\u00fc iyile\u015ftiriyor mu?" sorusuna yan\u0131t verecek bir deneme yapman\u0131n m\u00fcmk\u00fcn oldu\u011funu g\u00f6sterdik.\u201c<\/p>\n

\u0130ngiltere'nin \u00fc\u00e7 b\u00f6lgesindeki 84 aile hekimli\u011fi klini\u011finden 2 ya\u015f\u0131ndan k\u00fc\u00e7\u00fck, egzama tan\u0131s\u0131 konmu\u015f 493 \u00e7ocu\u011fu \u00e7al\u0131\u015fmaya dahil edece\u011fiz. \u00c7ocuklar rastgele iki gruba ayr\u0131lacak: "ola\u011fan bak\u0131m" ve m\u00fcdahale grubu. M\u00fcdahale grubundaki \u00e7ocuklara, yayg\u0131n olarak alerjiye neden olan d\u00f6rt g\u0131da i\u00e7in deri prick testi uygulanacak: s\u00fct, yumurta, bu\u011fday ve soya.<\/p>\n

Test sonu\u00e7lar\u0131na ba\u011fl\u0131 olarak, ebeveynlere 1 ay boyunca bir veya daha fazla yiyece\u011fi diyetlerinden \u00e7\u0131karmalar\u0131 veya diyetlerine eklemeleri tavsiye edilecektir. Sonu\u00e7lar\u0131 net olmayan \u00e7ocuklar, yerel alerji kliniklerinde s\u00f6z konusu yiyece\u011fi yerken g\u00f6zlemlenecektir.<\/p>\n

Temel sonu\u00e7 \u00f6l\u00e7\u00fct\u00fcm\u00fcz, ebeveynler taraf\u0131ndan bildirilen egzama kontrol\u00fcd\u00fcr. Ebeveynlerden bir y\u0131l boyunca her ay anket doldurmalar\u0131n\u0131 isteyece\u011fiz. \u00c7ocuklar\u0131n ciltlerini temel sonu\u00e7 \u00f6l\u00e7\u00fct\u00fcn\u00fcn ba\u015flang\u0131c\u0131nda ve sonunda (6 ay) de\u011ferlendirece\u011fiz. Ayr\u0131ca \u00e7ocuklar\u0131n ya\u015fam kalitesini, beslenme \u00e7e\u015fitlili\u011fini ve b\u00fcy\u00fcmesini de \u00f6l\u00e7ece\u011fiz.<\/p>\n

Paran\u0131n kar\u015f\u0131l\u0131\u011f\u0131n\u0131 de\u011ferlendirmek i\u00e7in sa\u011fl\u0131k ve bak\u0131m maliyetlerini toplayaca\u011f\u0131z. Ayr\u0131ca t\u00fck\u00fcr\u00fck \u00f6rnekleri toplayarak genetik risk fakt\u00f6rlerini ara\u015ft\u0131rmak i\u00e7in e\u015fsiz bir f\u0131rsat sunacak.<\/p>\n

Test sonu\u00e7lar\u0131na dayanarak \u00e7ocuklar\u0131n beslenme d\u00fczeninde de\u011fi\u015fiklik yapmak karma\u015f\u0131k bir s\u00fcre\u00e7tir, bu nedenle i\u015fleyi\u015fi de\u011ferlendirmek i\u00e7in bir "s\u00fcre\u00e7 de\u011ferlendirmesi" yapaca\u011f\u0131z. Bu, ara\u015ft\u0131rman\u0131n y\u00fcr\u00fct\u00fclme \u015feklini g\u00f6zlemlemeyi ve baz\u0131 kat\u0131l\u0131mc\u0131larla g\u00f6r\u00fc\u015fmeyi i\u00e7erecektir.<\/p>\n

Ara\u015ft\u0131rmay\u0131 kim y\u00fcr\u00fct\u00fcyor?<\/h2>\n

Profes\u00f6r Matthew Ridd<\/a>, Bristol \u00dcniversitesi Birinci Basamak Sa\u011fl\u0131k Hizmetleri Profes\u00f6r\u00fc.<\/p>\n

Daha fazla bilgi:<\/h2>\n

Daha fazla bilgi almak veya bu projeye kat\u0131lmak i\u00e7in l\u00fctfen e-posta g\u00f6nderin. bnssg.research@nhs.net<\/a>.<\/p>\n

Burada ifade edilen g\u00f6r\u00fc\u015fler yazar(lar)a aittir ve NIHR veya Sa\u011fl\u0131k ve Sosyal Bak\u0131m Bakanl\u0131\u011f\u0131'n\u0131n g\u00f6r\u00fc\u015flerini yans\u0131tmayabilir.<\/p>\n <\/div>\r\n <\/section><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"

Section titled module-1 Trial of IGe tests for Eczema Relief (TIGER).   Funding: National Institute for Health and Care Research (NIHR), Health Technology Assessment (HTA) Ref. NIHR133464. What is the research question? Does dietary advice based on routine food allergy tests improve disease control compared with usual care in children with eczema? What is the […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":32881,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"tags":[],"class_list":["post-34557","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/tr\/wp-json\/wp\/v2\/pages\/34557","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/tr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/tr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/tr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/tr\/wp-json\/wp\/v2\/comments?post=34557"}],"version-history":[{"count":3,"href":"https:\/\/bnssghealthiertogether.org.uk\/tr\/wp-json\/wp\/v2\/pages\/34557\/revisions"}],"predecessor-version":[{"id":36182,"href":"https:\/\/bnssghealthiertogether.org.uk\/tr\/wp-json\/wp\/v2\/pages\/34557\/revisions\/36182"}],"up":[{"embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/tr\/wp-json\/wp\/v2\/pages\/32881"}],"wp:attachment":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/tr\/wp-json\/wp\/v2\/media?parent=34557"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/tr\/wp-json\/wp\/v2\/tags?post=34557"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}