{"id":34548,"date":"2024-11-26T16:46:57","date_gmt":"2024-11-26T16:46:57","guid":{"rendered":"https:\/\/bnssghealthiertogether.org.uk\/?page_id=34548"},"modified":"2025-01-16T22:41:05","modified_gmt":"2025-01-16T22:41:05","slug":"the-effectiveness-and-cost-effectiveness-of-coenzyme-q10-in-heart-failure-with-reduced-ejection-fraction-a-pragmatic-patient-centred-data-enabled-trial-in-primary-care-coral","status":"publish","type":"page","link":"https:\/\/bnssghealthiertogether.org.uk\/ur\/integrated-care-board\/research-and-evidence\/our-research-portfolio\/nihr-funded-projects\/the-effectiveness-and-cost-effectiveness-of-coenzyme-q10-in-heart-failure-with-reduced-ejection-fraction-a-pragmatic-patient-centred-data-enabled-trial-in-primary-care-coral\/","title":{"rendered":"\u06a9\u0645 \u0627\u0646\u062c\u06cc\u06a9\u0634\u0646 \u0641\u0631\u06cc\u06a9\u0634\u0646 \u06a9\u06d2 \u0633\u0627\u062a\u06be \u062f\u0644 \u06a9\u06cc \u0646\u0627\u06a9\u0627\u0645\u06cc \u0645\u06cc\u06ba coenzyme Q10 \u06a9\u06cc \u062a\u0627\u062b\u06cc\u0631 \u0627\u0648\u0631 \u0644\u0627\u06af\u062a \u06a9\u06cc \u062a\u0627\u062b\u06cc\u0631: \u067e\u0631\u0627\u0626\u0645\u0631\u06cc \u06a9\u06cc\u0626\u0631 (CORAL) \u0645\u06cc\u06ba \u0627\u06cc\u06a9 \u0639\u0645\u0644\u06cc\u060c \u0645\u0631\u06cc\u0636 \u067e\u0631 \u0645\u0628\u0646\u06cc\u060c \u0688\u06cc\u0679\u0627 \u0633\u06d2 \u0686\u0644\u0646\u06d2 \u0648\u0627\u0644\u0627 \u0679\u0631\u0627\u0626\u0644\u06d4"},"content":{"rendered":"<div class=\"assembler_default-group assembler_module_group assembler_default-group_1 assembler_module_group_1\"><div class=\"assembler_module_area assembler_module_area_1\"><div class=\"assembler_text-module assembler_module assembler_text-module_1 assembler_module_1  transparent\"><a tabindex=\"-1\" title=\"\u0633\u06cc\u06a9\u0634\u0646 \u062c\u0633 \u06a9\u0627 \u0639\u0646\u0648\u0627\u0646 \u0645\u0627\u0688\u06cc\u0648\u0644-1 \u06c1\u06d2\" id=\"module-1\" href=\"https:\/\/bnssghealthiertogether.org.uk\/ur\/wp-json\/wp\/v2\/pages\/34548\/#module-1\" class=\"anchor\"><span class=\"hidden\">\u0633\u06cc\u06a9\u0634\u0646 \u062c\u0633 \u06a9\u0627 \u0639\u0646\u0648\u0627\u0646 \u0645\u0627\u0688\u06cc\u0648\u0644-1 \u06c1\u06d2<\/span><\/a><!-- Template found for text-module - Template: template-text - Matched: _only --><section class=\"w-full mx-auto max-w-content pt-12 sm:pt-24 pb-12 sm:pb-24\">\r\n  <div class=\"entry-content w-full !px-0 max-w-small\">\r\n        <h1>\u062f\u0644 \u06a9\u06cc \u0646\u0627\u06a9\u0627\u0645\u06cc \u0645\u06cc\u06ba coenzyme Q10 \u06a9\u06cc \u062a\u0627\u062b\u06cc\u0631 \u0627\u0648\u0631 \u0644\u0627\u06af\u062a \u06a9\u06cc \u062a\u0627\u062b\u06cc\u0631 \u0645\u06cc\u06ba \u06a9\u0645\u06cc \u06a9\u06d2 \u0633\u0627\u062a\u06be<br \/>\n\u0627\u0646\u062c\u06cc\u06a9\u0634\u0646 \u0641\u0631\u06cc\u06a9\u0634\u0646: \u067e\u0631\u0627\u0626\u0645\u0631\u06cc \u06a9\u06cc\u0626\u0631 \u0645\u06cc\u06ba \u0627\u06cc\u06a9 \u0639\u0645\u0644\u06cc\u060c \u0645\u0631\u06cc\u0636 \u067e\u0631 \u0645\u0628\u0646\u06cc\u060c \u0688\u06cc\u0679\u0627 \u0633\u06d2 \u0686\u0644\u0646\u06d2 \u0648\u0627\u0644\u0627 \u0679\u0631\u0627\u0626\u0644 (CORAL)<\/h1>\n<p>&nbsp;<\/p>\n<article class=\"page_content\">\n<h2 class=\"page_content__inner\">\u0641\u0646\u0688\u0646\u06af<\/h2>\n<\/article>\n<p>\u0646\u06cc\u0634\u0646\u0644 \u0627\u0646\u0633\u0679\u06cc \u0679\u06cc\u0648\u0679 \u0641\u0627\u0631 \u06c1\u06cc\u0644\u062a\u06be \u0627\u06cc\u0646\u0688 \u06a9\u06cc\u0626\u0631 \u0631\u06cc\u0633\u0631\u0686 (NIHR) \u06c1\u06cc\u0644\u062a\u06be \u0679\u06cc\u06a9\u0646\u0627\u0644\u0648\u062c\u06cc \u0627\u0633\u06cc\u0633\u0645\u0646\u0679 (HTA) Ref. NIHR152257\u06d4.<\/p>\n<h2>\u0645\u0633\u0626\u0644\u06c1 \u06a9\u06cc\u0627 \u06c1\u06d2\u061f<\/h2>\n<p>\u062f\u0644 \u06a9\u06cc \u0646\u0627\u06a9\u0627\u0645\u06cc \u06a9\u0627 \u0645\u0637\u0644\u0628 \u06c1\u06d2 \u06a9\u06c1 \u062f\u0644 \u062e\u0648\u0646 \u06a9\u0648 \u0679\u06be\u06cc\u06a9 \u0637\u0631\u06cc\u0642\u06d2 \u0633\u06d2 \u067e\u0645\u067e \u0646\u06c1\u06cc\u06ba \u06a9\u0631 \u0633\u06a9\u062a\u0627 \u06a9\u06cc\u0648\u0646\u06a9\u06c1 \u06cc\u06c1 \u0628\u06c1\u062a \u06a9\u0645\u0632\u0648\u0631 \u06cc\u0627 \u0628\u06c1\u062a \u0633\u062e\u062a \u06c1\u06d2\u06d4 \u062f\u0644 \u06a9\u06cc \u0646\u0627\u06a9\u0627\u0645\u06cc \u0648\u0627\u0644\u06d2 \u0644\u0648\u06af \u0627\u06a9\u062b\u0631 \u0633\u0627\u0646\u0633 \u06a9\u06cc \u0642\u0644\u062a \u0627\u0648\u0631 \u062a\u06be\u06a9\u0627\u0648\u0679 \u0645\u062d\u0633\u0648\u0633 \u06a9\u0631\u062a\u06d2 \u06c1\u06cc\u06ba\u06d4 \u0627\u0646 \u06a9\u06d2 \u067e\u0627\u0624\u06ba \u0627\u0648\u0631 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\u0632\u0646\u062f\u06af\u06cc \u06a9\u06d2 \u0645\u0639\u06cc\u0627\u0631 \u06a9\u0648 \u0628\u06c1\u062a\u0631 \u0628\u0646\u0627\u062a\u0627 \u06c1\u06d2\u06d4 Coenzyme Q10 \u0627\u06cc\u06a9 \u0648\u0679\u0627\u0645\u0646 \u0646\u0645\u0627 \u0645\u0627\u062f\u06c1 \u06c1\u06d2 \u062c\u0648 \u0642\u062f\u0631\u062a\u06cc \u0637\u0648\u0631 \u067e\u0631 \u062c\u0633\u0645 \u0645\u06cc\u06ba \u0627\u0648\u0631 \u06a9\u0686\u06be \u06a9\u06be\u0627\u0646\u0648\u06ba \u0645\u06cc\u06ba \u067e\u0627\u06cc\u0627 \u062c\u0627\u062a\u0627 \u06c1\u06d2\u06d4.<\/p>\n<p>\u06c1\u0645 \u06cc\u06c1 \u062c\u0627\u0646\u0646\u06d2 \u06a9\u06d2 \u0644\u06cc\u06d2 \u0627\u06cc\u06a9 \u0645\u0637\u0627\u0644\u0639\u06c1 \u06a9\u0631\u0646\u0627 \u0686\u0627\u06c1\u062a\u06d2 \u06c1\u06cc\u06ba \u06a9\u06c1 \u06a9\u06cc\u0627 coenzyme Q10 \u0644\u06cc\u0646\u0627 \u0627\u0646 \u0644\u0648\u06af\u0648\u06ba \u06a9\u06d2 \u0644\u06cc\u06d2 \u0641\u0627\u0626\u062f\u06c1 \u0645\u0646\u062f \u06c1\u06d2 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\u0627\u0648\u0631 \u0627\u0646 \u06a9\u06cc \u062f\u06cc\u06a9\u06be \u0628\u06be\u0627\u0644 \u06a9\u0631\u0646\u06d2 \u0648\u0627\u0644\u0648\u06ba \u06a9\u0648 \u0645\u0627\u0644\u06cc \u0637\u0648\u0631 \u067e\u0631 \u06a9\u06cc\u0633\u06d2 \u0645\u062a\u0627\u062b\u0631 \u06a9\u0631\u062a\u06cc \u06c1\u06d2\u06d4 \u0645\u0637\u0627\u0644\u0639\u06c1 \u0645\u06cc\u06ba \u062d\u0635\u06c1 \u0644\u06cc\u0646\u06d2 \u0648\u0627\u0644\u06d2 \u0644\u0648\u06af\u0648\u06ba \u0633\u06d2 \u0645\u0637\u0627\u0644\u0639\u06c1 \u0634\u0631\u0648\u0639 \u06c1\u0648\u0646\u06d2 \u0633\u06d2 \u067e\u06c1\u0644\u06d2\u060c \u067e\u06be\u0631 3\u060c 6\u060c 9 \u0645\u0627\u06c1 \u0627\u0648\u0631 \u0627\u06cc\u06a9 \u0633\u0627\u0644 (\u062c\u0628 \u0645\u0637\u0627\u0644\u0639\u06c1 \u062e\u062a\u0645 \u06c1\u0648 \u062c\u0627\u0626\u06d2 \u06af\u0627) \u0627\u0646 \u0633\u0648\u0627\u0644\u0646\u0627\u0645\u0648\u06ba \u06a9\u0648 \u0628\u06be\u0631\u0646\u06d2 \u06a9\u06d2 \u0644\u06cc\u06d2 \u06a9\u06c1\u0627 \u062c\u0627\u0626\u06d2 \u06af\u0627\u06d4.<\/p>\n<p>\u06c1\u0645\u0627\u0631\u06d2 \u062e\u06cc\u0627\u0644 \u0645\u06cc\u06ba \u0633\u0648\u0627\u0644\u0646\u0627\u0645\u0648\u06ba \u06a9\u0648 \u0628\u06be\u0631\u0646\u06d2 \u0645\u06cc\u06ba \u062a\u0642\u0631\u06cc\u0628\u0627\u064b 35 \u0645\u0646\u0679 \u0644\u06af\u06cc\u06ba \u06af\u06d2 \u0627\u0648\u0631 \u06c1\u0645 \u0633\u0648\u0627\u0644\u0646\u0627\u0645\u0648\u06ba \u06a9\u06d2 \u06c1\u0631 \u0633\u06cc\u0679 \u06a9\u06d2 \u0644\u06cc\u06d2 \u0644\u0648\u06af\u0648\u06ba \u06a9\u0648 \u0627\u0646 \u06a9\u06d2 \u0648\u0642\u062a \u06a9\u06d2 \u0644\u06cc\u06d2 \u00a310 \u06a9\u0627 \u0645\u0639\u0627\u0648\u0636\u06c1 \u062f\u06cc\u06ba \u06af\u06d2\u06d4.<\/p>\n<p>\u0627\u062c\u0627\u0632\u062a \u06a9\u06d2 \u0633\u0627\u062a\u06be\u060c \u06c1\u0645 \u0635\u062d\u062a \u06a9\u06cc \u062f\u06cc\u06a9\u06be \u0628\u06be\u0627\u0644 \u06a9\u06cc \u062a\u0642\u0631\u0631\u06cc\u0648\u06ba\u060c \u06c1\u0633\u067e\u062a\u0627\u0644 \u0645\u06cc\u06ba \u062f\u0627\u062e\u0644\u06d2 \u0627\u0648\u0631 \u0628\u0642\u0627 \u06a9\u06d2 \u0628\u0627\u0631\u06d2 \u0645\u06cc\u06ba \u062c\u0627\u0646\u0646\u06d2 \u06a9\u06d2 \u0644\u06cc\u06d2 \u0627\u0646 \u06a9\u0627 \u0645\u06cc\u0688\u06cc\u06a9\u0644 \u0631\u06cc\u06a9\u0627\u0631\u0688 \u0627\u0633\u062a\u0639\u0645\u0627\u0644 \u06a9\u0631\u06cc\u06ba \u06af\u06d2\u06d4 \u062f\u0644 \u06a9\u06cc \u0646\u0627\u06a9\u0627\u0645\u06cc \u0648\u0627\u0644\u06d2 \u0644\u0648\u06af\u0648\u06ba \u06a9\u06d2 \u0644\u06cc\u06d2 \u0645\u0637\u0627\u0644\u0639\u06c1 \u0645\u06cc\u06ba \u062d\u0635\u06c1 \u0644\u06cc\u0646\u0627 \u0622\u0633\u0627\u0646 \u0628\u0646\u0627\u0646\u06d2 \u06a9\u06d2 \u0644\u06cc\u06d2\u060c \u06c1\u0645 \u0627\u0646 \u0633\u06d2 \u06a9\u0633\u06cc \u0628\u06be\u06cc \u0645\u0637\u0627\u0644\u0639\u0627\u062a\u06cc \u062f\u0648\u0631\u0648\u06ba \u06a9\u06d2 \u0644\u06cc\u06d2 \u0627\u0646 \u06a9\u06d2 \u06c1\u0633\u067e\u062a\u0627\u0644 \u06cc\u0627 GP \u067e\u0631\u06cc\u06a9\u0679\u0633 \u0645\u06cc\u06ba \u0634\u0631\u06a9\u062a \u06a9\u06d2 \u0644\u06cc\u06d2 \u0646\u06c1\u06cc\u06ba \u06a9\u06c1\u06cc\u06ba \u06af\u06d2\u06d4.<\/p>\n<p>\u0627\u0646\u06c1\u06cc\u06ba \u0645\u0637\u0627\u0644\u0639\u06c1 \u06a9\u06d2 \u0628\u0627\u0631\u06d2 \u0645\u06cc\u06ba \u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0628\u0630\u0631\u06cc\u0639\u06c1 \u0688\u0627\u06a9 \u0628\u06be\u06cc\u062c\u06cc \u062c\u0627\u0626\u06cc\u06ba \u06af\u06cc\u060c \u0627\u0646 \u06a9\u0627 \u062c\u06cc \u067e\u06cc \u06cc\u0627 \u0646\u0631\u0633 \u0627\u0646\u06c1\u06cc\u06ba \u0641\u0648\u0646 \u06a9\u0631\u06a9\u06d2 \u0645\u0637\u0627\u0644\u0639\u06c1 \u06a9\u06cc \u0648\u0636\u0627\u062d\u062a \u06a9\u0631\u06d2 \u06af\u06cc \u0627\u0648\u0631 \u0627\u0646 \u06a9\u06cc \u0645\u0637\u0627\u0644\u0639\u06c1 \u06a9\u06cc \u062f\u0648\u0627\u0626\u06cc\u06ba \u0628\u0631\u0627\u06c1 \u0631\u0627\u0633\u062a \u0627\u0646 \u06a9\u06d2 \u06af\u06be\u0631 \u0628\u06be\u06cc\u062c \u062f\u06cc \u062c\u0627\u0626\u06cc\u06ba \u06af\u06cc\u06d4.<\/p>\n<p>\u0645\u0637\u0627\u0644\u0639\u06c1 \u0645\u06cc\u06ba \u062d\u0635\u06c1 \u0644\u06cc\u0646\u06d2 \u0648\u0627\u0644\u06d2 \u0627\u0641\u0631\u0627\u062f \u06a9\u06d2 \u067e\u0627\u0633 \u0627\u067e\u0646\u06d2 \u0633\u0648\u0627\u0644\u0646\u0627\u0645\u06d2 \u0645\u06a9\u0645\u0644 \u06a9\u0631\u0646\u06d2 \u06a9\u06d2 \u0644\u06cc\u06d2 \u06a9\u0626\u06cc \u0627\u062e\u062a\u06cc\u0627\u0631\u0627\u062a \u06c1\u0648\u06ba \u06af\u06d2: \u0622\u0646 \u0644\u0627\u0626\u0646\u060c \u0679\u06cc\u0644\u06cc \u0641\u0648\u0646 \u06a9\u06d2 \u0630\u0631\u06cc\u0639\u06d2 \u06cc\u0627 \u0627\u067e\u0646\u06d2 GP \u067e\u0631\u06cc\u06a9\u0679\u0633 \u0645\u06cc\u06ba \u0622\u0645\u0646\u06d2 \u0633\u0627\u0645\u0646\u06d2\u06d4.<\/p>\n<h2>\u062a\u062d\u0642\u06cc\u0642 \u06a9\u06cc \u0642\u06cc\u0627\u062f\u062a \u06a9\u0648\u0646 \u06a9\u0631 \u0631\u06c1\u0627 \u06c1\u06d2\u061f<\/h2>\n<p><a href=\"https:\/\/www.bristol.ac.uk\/people\/person\/Maria-Pufulete-6812e04e-f4da-448d-91db-032c4eddd93a\/\" rel=\"noopener\">\u0688\u0627\u06a9\u0679\u0631 \u0645\u0627\u0631\u06cc\u06c1 \u067e\u0641\u0644\u06cc\u0679<\/a>, \u060c \u0633\u06cc\u0646\u0626\u0631 \u0631\u06cc\u0633\u0631\u0686 \u0641\u06cc\u0644\u0648\u060c \u0628\u0631\u0633\u0679\u0644 \u06cc\u0648\u0646\u06cc\u0648\u0631\u0633\u0679\u06cc \u0627\u0648\u0631 <a href=\"https:\/\/www.bristol.ac.uk\/people\/person\/Rachel-Johnson-76214692-715a-441e-b67a-cfd9acdfa97a\/\" rel=\"noopener\">\u0688\u0627\u06a9\u0679\u0631 \u0631\u06cc\u0686\u0644 \u062c\u0627\u0646\u0633\u0646<\/a>, \u060c \u067e\u0631\u0627\u0626\u0645\u0631\u06cc \u06a9\u06cc\u0626\u0631 \u0645\u06cc\u06ba \u0627\u06cc\u0633\u0648\u0633\u06cc \u0627\u06cc\u0679 \u067e\u0631\u0648\u0641\u06cc\u0633\u0631\u060c \u0628\u0631\u0633\u0679\u0644 \u06cc\u0648\u0646\u06cc\u0648\u0631\u0633\u0679\u06cc\u06d4.<\/p>\n<h2>\u0645\u0632\u06cc\u062f \u0645\u0639\u0644\u0648\u0645\u0627\u062a:<\/h2>\n<p>\u0645\u0632\u06cc\u062f \u0645\u0639\u0644\u0648\u0645\u0627\u062a \u06a9\u06d2 \u0644\u06cc\u06d2 \u06cc\u0627 \u0627\u0633 \u067e\u0631\u0648\u062c\u06cc\u06a9\u0679 \u0645\u06cc\u06ba \u0634\u0627\u0645\u0644 \u06c1\u0648\u0646\u06d2 \u06a9\u06d2 \u0644\u06cc\u06d2 \u0627\u06cc \u0645\u06cc\u0644 \u06a9\u0631\u06cc\u06ba\u06d4 <a href=\"mailto:bnssg.research@nhs.net\" target=\"_blank\" rel=\"noopener\">bnssg.research@nhs.net<\/a>.<\/p>\n<p>\u062c\u0646 \u062e\u06cc\u0627\u0644\u0627\u062a \u06a9\u0627 \u0627\u0638\u06c1\u0627\u0631 \u06a9\u06cc\u0627 \u06af\u06cc\u0627 \u06c1\u06d2 \u0648\u06c1 \u0645\u0635\u0646\u0641\u06cc\u0646 \u06a9\u06d2 \u06c1\u06cc\u06ba \u0627\u0648\u0631 \u0636\u0631\u0648\u0631\u06cc \u0646\u06c1\u06cc\u06ba \u06a9\u06c1 \u0648\u06c1 NIHR \u06cc\u0627 \u0645\u062d\u06a9\u0645\u06c1 \u0635\u062d\u062a \u0627\u0648\u0631 \u0633\u0645\u0627\u062c\u06cc \u0646\u06af\u06c1\u062f\u0627\u0634\u062a \u06a9\u06d2 \u06c1\u0648\u06ba\u06d4.<\/p>\n  <\/div>\r\n  <\/section><\/div><!-- .assembler_text-module.assembler_module.assembler_text-module_1.assembler_module_1..transparent --><\/div><!-- .assembler_module_area.assembler_module_area_1 --><\/div><!-- .assembler_default-group.assembler_module_group.assembler_default-group_1.assembler_module_group_1  -->","protected":false},"excerpt":{"rendered":"<p>Section titled module-1 The effectiveness and cost effectiveness of coenzyme Q10 in heart failure with reduced ejection fraction: a pragmatic, patient-centred, data-enabled trial in primary care (CORAL) &nbsp; Funding National Institute for Health and Care Research (NIHR) Health Technology Assessment (HTA) Ref. NIHR152257. What is the problem? Heart failure means the heart can\u2019t pump blood [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":32881,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"tags":[],"class_list":["post-34548","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/ur\/wp-json\/wp\/v2\/pages\/34548","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/ur\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/ur\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/ur\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/ur\/wp-json\/wp\/v2\/comments?post=34548"}],"version-history":[{"count":3,"href":"https:\/\/bnssghealthiertogether.org.uk\/ur\/wp-json\/wp\/v2\/pages\/34548\/revisions"}],"predecessor-version":[{"id":36179,"href":"https:\/\/bnssghealthiertogether.org.uk\/ur\/wp-json\/wp\/v2\/pages\/34548\/revisions\/36179"}],"up":[{"embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/ur\/wp-json\/wp\/v2\/pages\/32881"}],"wp:attachment":[{"href":"https:\/\/bnssghealthiertogether.org.uk\/ur\/wp-json\/wp\/v2\/media?parent=34548"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bnssghealthiertogether.org.uk\/ur\/wp-json\/wp\/v2\/tags?post=34548"}],"curies":[{"name":"\u0688\u0628\u0644\u06cc\u0648 \u067e\u06cc","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}